We are developing nanoparticles to redirect stem cells to the injured heart
We have proposed a new model of how cells leave the blood vessels called angiopellosis.
We have many members in the lab including undergraduates, graduate students, postdoctoral researchers, and visiting researchers of many different research backgrounds.
The regenerative potential of lung stem cells has been demonstrated in rodent models of lung injury. Learn more.
Our research was recently featured on the cover of Circulation Research
Synthetic stem cells show therapeutic potential.
The BioTherapeutics Laboratory is led by Dr. Ke Cheng and is a part of the Department of Molecular and Biomedical Sciences at the North Carolina State University College of Veterinary Medicine as well as the Joint Department of Biomedical Engineering at the University of North Carolina at Chapel Hill and North Carolina State University. Our studies include regenerative medicine approaches by using patient-derived stem cells, biomaterials, and targeted nanoparticles. For stem cell research, we are interested in isolating patient-specific and organ-specific adult stem cells and testing their regenerative potential in small/large animal models of diseases. We are also taking an integrated approach that combines cells, biomaterials, nanoparticles, and other bioengineering approaches such as magnetic targeting to enhance the efficiency of stem cell therapies.